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The Challenges of Complex Sample Analysis – How to Stay Ahead with FTMS

Customers – working in advanced fields like proteomics and metabolomics – tell us two of the limiting factors in their research are mass spec sensitivity and resolving power. And while speed remains...

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solariX XR – Top Down Protein Analysis With MS

Mass spectrometry and tandem mass spectrometry have found wide application to the analysis of proteins and proteomes. However, some proteins cannot be identified by bottom-up mass spectrometry...

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How to Successfully Navigate an Integrated Omics Campaign

Emerging Technology to Realize the Promise of Integrated Omics Mass spectrometry has provided the technological foundation on which experimental omics has been based. A range of mass spec (MS)...

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Mass Spec – Top-Down Characterization of Glycoproteins

One of our team members – Marcus Macht – over in Bremen, Germany recently published a paper in TrAC (Trends in Analytical Chemistry) highlighting success with top-down characterization using Bruker’s...

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BioPharma Compass – The Next Generation of Biopharmaceutical Characterization

Biopharmaceutical Characterization – a Single, Seamless Process. There are a couple of ways researchers can approach the process of characterizing a biopharmaceutical: for example, it can be...

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Upcoming Free Mass Spec Webinar & Live Q&A

Rapid, Accurate Profiling of Small Molecules Using Ultra-High Resolution Mass Spectrometry Exciting News! We will be sponsoring a webinar on the identification of small molecule impurities and drug...

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MALDI Imaging Success Stories in Clinical Research: Hepatocellular Cancer

Part I of our 3-part MALDI Imaging Success Stories kicks off with hepatocellular carcinoma – also called malignant hepatoma. It’s the most common type of liver cancer (which, by the way, is fairly...

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Mass Spec Goes High Def

High Definition delivers phenomenal high-resolution results for complex-sample metabolomics, biomarker identification, top-down protein analysis and quantitative target compound validation. Back in...

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Mass Spec Rapid Compound Screening – Is Your Food Safe Enough to Eat?

Two weeks ago, I posted about Rapid Drug Screening: Today’s Need for Speed … and Reliability. When it comes to mass spectrometry, what’s good for detecting amphetamines is also the perfect solution...

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Mass Spectrometry: Beyond our Wildest Dreams

Did you know that Moore’s Law was recently modified? Back in the 1960’s – when Moore’s law was created – it stipulated that computer performance would double every 18-24 months…which it did for fifty...

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MALDI Biotyper: Goodbye Biochemical Assays, Hello Faster & Simpler Microbiology!

Microbiology – the study of microscopic organisms – isn’t quite ready to wave goodbye to the microscope just yet, but it is making some space next to it on the lab bench. The latest tool to take over...

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MALDI Imaging Success Stories in Clinical Research: Osoephagal Cancer

Learn how researchers used mass spectrometry – a MALDI imaging unit- to identify a protein (COX7-A2) that could be targeted during treatment to deliver drugs specifically to tumor cells. Barrets...

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Happy 2014!

Happy New Year! I’d like to start January off by providing some useful links and random thoughts: First off, did you spend part of Christmas trying to explain mass spectrometry to an 11-year old niece...

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PRIME: Deconstructing the Proteome

In the good old days – back at the start of the proteomics revolution 15 or 20 years ago – it was generally thought that that characterizing the proteome was just a few years away. But the proteome...

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Webinar: Identification of Microorganisms using MALDI-TOF

Don’t miss this free webinar (on 6th February 2014: 8am PST / 11am EST / 4pm GMT / 5pm CET) detailing how Genzyme has implemented MALDI-TOF to identify microorganisms in a QC microbiology laboratory....

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Metabolomics Profiling Yields Valuable Clues to an Organism’s Physiology

Metabolomic Profiler: a fully-integrated Bruker metabolomics system based on NMR and MS Comprehensive metabolomic profiling can serve as a window into the physiological functioning of an organism....

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Ion Trap – the Workhorse of Mass Specs

We’ve done a few posts about the power and versatility of Ion Trap mass spec, and we still sometimes field questions with a common theme:  Is Ion Trap still a really good technology? How good is Ion...

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Ionization: Choosing the Correct API Technique for Optimal Results

Back in an August post on proteomics, we mentioned Bruker’s CaptiveSpray nanoBooster™  ion source, which helps boost peptide ID rates in complex proteomics samples. Getting quality data is all about...

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Bruker Mass Spec Wrap-Up: Last Chance at a Great QTOF Deal; New YouTube...

Before we forget, March is the last chance for our EU and US customers to get a great deal on a refurbished, warrantied, state-of-the-art Bruker maXis plus UHR-QTOF. This deal delivers a...

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Quantitative and Qualitative Strategies for Targeted and Non-Targeted...

Targeted and Non-Targeted Metabolomics – Difficult to Strategize? Developing specific strategies for both targeted metabolomics studies can be challenging. And non-targeted studies? Historically, it’s...

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